A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos | Journal of Medicinal Chemistry
![Controversy regarding the functional conservation of cereblon CUL4-type E3 ligase substrate receptor Controversy regarding the functional conservation of cereblon CUL4-type E3 ligase substrate receptor](https://www.oatext.com/img/ICST-5-283-g002.gif)
Controversy regarding the functional conservation of cereblon CUL4-type E3 ligase substrate receptor
![Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine](https://www.frontiersin.org/files/MyHome%20Article%20Library/629326/629326_Thumb_400.jpg)
Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine
![The Ubiquitination-Dependent and -Independent Functions of Cereblon in Cancer and Neurological Diseases - ScienceDirect The Ubiquitination-Dependent and -Independent Functions of Cereblon in Cancer and Neurological Diseases - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0022283622000213-ga1.jpg)
The Ubiquitination-Dependent and -Independent Functions of Cereblon in Cancer and Neurological Diseases - ScienceDirect
![Cereblon and its downstream substrates as molecular targets of immunomodulatory drugs | SpringerLink Cereblon and its downstream substrates as molecular targets of immunomodulatory drugs | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs12185-016-2073-4/MediaObjects/12185_2016_2073_Fig4_HTML.gif)
Cereblon and its downstream substrates as molecular targets of immunomodulatory drugs | SpringerLink
![Target degradation landscape of clinical cereblon modulators. (A) A... | Download Scientific Diagram Target degradation landscape of clinical cereblon modulators. (A) A... | Download Scientific Diagram](https://www.researchgate.net/publication/362078169/figure/fig4/AS:11431281078842564@1660278171281/Target-degradation-landscape-of-clinical-cereblon-modulators-A-A-graphical-model-of.png)
Target degradation landscape of clinical cereblon modulators. (A) A... | Download Scientific Diagram
![A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer - ScienceDirect A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S004520682100883X-ga1.jpg)
A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer - ScienceDirect
![Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine](https://www.frontiersin.org/files/Articles/629326/fcell-09-629326-HTML/image_m/fcell-09-629326-g002.jpg)
Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine
![Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology - ScienceDirect Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2451945621002051-fx1.jpg)
Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology - ScienceDirect
![CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells - ScienceDirect CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0006497121002160-grabsf1.jpg)
CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells - ScienceDirect
![Cancers | Free Full-Text | Rapid Progress in the Use of Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in the Treatment of Multiple Myeloma Cancers | Free Full-Text | Rapid Progress in the Use of Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in the Treatment of Multiple Myeloma](https://www.mdpi.com/cancers/cancers-13-04666/article_deploy/html/images/cancers-13-04666-g003.png)
Cancers | Free Full-Text | Rapid Progress in the Use of Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in the Treatment of Multiple Myeloma
![Cereblon: A Protein Crucial to the Multiple Functions of Immunomodulatory Drugs as well as Cell Metabolism and Disease Generation Cereblon: A Protein Crucial to the Multiple Functions of Immunomodulatory Drugs as well as Cell Metabolism and Disease Generation](https://static-02.hindawi.com/articles/jir/volume-2017/9130608/figures/9130608.fig.001.jpg)
Cereblon: A Protein Crucial to the Multiple Functions of Immunomodulatory Drugs as well as Cell Metabolism and Disease Generation
![Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality | ACS Medicinal Chemistry Letters Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality | ACS Medicinal Chemistry Letters](https://pubs.acs.org/cms/10.1021/acsmedchemlett.9b00425/asset/images/large/ml9b00425_0001.jpeg)
Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality | ACS Medicinal Chemistry Letters
![Nature Portfolio auf Twitter: „A new cereblon modulator, CC-885, has been identified with potent anti-tumour activity https://t.co/fNxZ9K7ON5 https://t.co/FtnQXQ9dFr“ / Twitter Nature Portfolio auf Twitter: „A new cereblon modulator, CC-885, has been identified with potent anti-tumour activity https://t.co/fNxZ9K7ON5 https://t.co/FtnQXQ9dFr“ / Twitter](https://pbs.twimg.com/media/CmAnV5fWgAA8Puu.jpg)
Nature Portfolio auf Twitter: „A new cereblon modulator, CC-885, has been identified with potent anti-tumour activity https://t.co/fNxZ9K7ON5 https://t.co/FtnQXQ9dFr“ / Twitter
![CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia | Journal of Medicinal Chemistry CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/acs.jmedchem.0c01489/asset/images/medium/jm0c01489_0008.gif)
CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia | Journal of Medicinal Chemistry
![Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine](https://www.frontiersin.org/files/Articles/629326/fcell-09-629326-HTML/image_m/fcell-09-629326-g001.jpg)
Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine
![A Cereblon Modulator CC-885 Induces CRBN- and p97-Dependent PLK1 Degradation and Synergizes with Volasertib to Suppress Lung Cancer - ScienceDirect A Cereblon Modulator CC-885 Induces CRBN- and p97-Dependent PLK1 Degradation and Synergizes with Volasertib to Suppress Lung Cancer - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2372770520300929-fx1.jpg)